Poliosis
A comprehensive overview of poliosis, including causes, symptoms, diagnosis, treatment, and associated conditions.
Eyelid Disorder
Localized white eyelashes or eyebrows
Any age
Depends on the cause
Overview
Poliosis is the localized loss of melanin within hair follicles, resulting in white eyelashes, eyebrows, or scalp hair. It is a clinical sign that may occur with inflammatory eye disease, autoimmune disorders, genetic syndromes, infections, or medications. In ophthalmology, poliosis is commonly associated with chronic uveitis and Vogt-Koyanagi-Harada syndrome.
Symptoms & Signs
- White eyelashes or eyebrows
- Patchy depigmented hair
- Associated eyelid inflammation
- Possible uveitis symptoms
- Visual changes if underlying ocular disease is present
- Cosmetic concerns
Common Causes
- Chronic anterior uveitis
- Vogt-Koyanagi-Harada syndrome
- Vitiligo
- Alopecia areata
- Herpes zoster ophthalmicus
- Genetic syndromes (e.g., Waardenburg syndrome)
- Certain medications
Diagnosis
- Comprehensive eye examination
- External eyelid evaluation
- Slit-lamp examination
- Dilated fundus examination when uveitis is suspected
- Systemic evaluation based on associated findings
Differential Diagnosis
| Condition | Distinguishing Feature |
|---|---|
| Madarosis | Loss of eyelashes rather than depigmentation |
| Vitiligo | Skin depigmentation |
| Alopecia areata | Patchy hair loss |
| Blepharitis | Lid inflammation without pigment loss |
Treatment
- Treat the underlying condition
- Management of uveitis when present
- Dermatology referral when appropriate
- Cosmetic camouflage if desired
- Regular ophthalmic follow-up
Complications
- Progression of underlying disease
- Chronic ocular inflammation
- Vision loss from untreated uveitis
- Psychosocial concerns
Common ICD-10 Codes
| Code | Description |
|---|---|
| L67.1 | Variations in hair color (includes poliosis) |
| H20.9 | Uveitis, unspecified (common association) |
| L80 | Vitiligo |
Frequently Asked Questions
Is poliosis harmful?
Poliosis itself is harmless, but it may indicate an underlying ocular or systemic disorder that requires evaluation.
Can hair regain its normal color?
Sometimes, depending on the underlying cause. In many cases the color change may be permanent.
Medical Disclaimer
The information provided on Kardia Vision is for educational purposes only and should not replace professional medical advice, diagnosis, or treatment. Consult an eye care professional if you notice new white eyelashes, eyebrows, or associated eye inflammation.